Across TCGA pan-cancer cohorts, KRTAP20-2 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of KRTAP20-2’s most consistent transcriptional readouts.
The strongest signal is observed in lung squamous cell carcinoma (LUSC), where KRTAP20-2 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types KRTAP20-2 is over-expressed in tumor.
LUSC and PRAD are the cancer types where KRTAP20-2 tumor–normal differential expression is most reproducible.