Q-omics provides the consensus-scored KIAA2012 profile across patient tissues and cancer cell-line models. KIAA2012 expression is associated with patient survival in 20 of 34 cancer types, with the highest sampling consensus in ACC. Among the 18 cancer types available for tumor–normal comparison, KIAA2012 is differentially expressed in 9, with the highest sampling consensus in KICH. Additionally, KIAA2012 RNA expression shows 15,462 significant gene co-expression associations, with the highest sampling consensus in TGCT. Together, these results highlight ACC, KICH, and TGCT as cancer lineages where KIAA2012 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for KIAA2012 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes KIAA2012 survival associations across molecular data types. KIAA2012 RNA expression shows survival associations in the most cancer types (20), followed by mutation status (3). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible KIAA2012 RNA expression–survival associations across cancer types. High KIAA2012 expression shows unfavorable associations in ACC, KIRC, KIRP and LGG, but favorable associations in LIHC and DLBC. The ACC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify ACC as the clearest survival context for KIAA2012 RNA expression.
This table summarizes KIAA2012 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 9. The strongest signals are observed in KICH for RNA.
This table ranks reproducible tumor–normal expression differences for KIAA2012. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. KIAA2012 shows lower tumor expression in KICH, LUAD, LUSC and UCEC and higher tumor expression in COAD and STAD. The KICH box plot shows higher KIAA2012 RNA expression in normal versus tumor tissue (log2 FC = −0.044, t-test p < 0.001).
This table shows molecular features associated with KIAA2012 in patient tissues and cancer cell lines. In patient samples, KIAA2012 shows the broadest associations at the RNA and protein expression levels, with TGCT recurring as the lineage with the largest associated feature set. In cancer cell lines, KIAA2012 RNA and mutation anchors are most strongly linked to RNA-expression features, especially in KIDNEY, while CRISPR and shRNA rows add functional-dependency signals in STOMACH.
