KIAA2012

Across TCGA cell cohorts, KIAA2012 RNA expression is significantly associated with the go_rna of many other GO terms, with 866 significant associations in total. STOMACH shows the largest number of these associations.

The most reproducible KIAA2012-associated GO terms across cancer lineages are Retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum, Negative regulation of epidermal cell differentiation, and Negative regulation of epidermis development. Each is linked with KIAA2012 in more than 4 cancer types. Because this analysis shows association rather than direction, both KIAA2012-to-partner and partner-to-KIAA2012 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum grouped by KIAA2012-low versus KIAA2012-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KIAA2012→partner) and Y-score (partner→KIAA2012) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum →	+0.052	+0.016	<.001	.001	3	5
KIDNEY	Negative regulation of epidermal cell differentiation →	-0.143	-0.014	.001	.007	3	4
KIDNEY	Negative regulation of epidermis development →	-0.143	-0.014	.001	.007	3	4
STOMACH	Cellular response to epidermal growth factor stimulus →	+0.093	+0.078	.006	.004	3	4
LARGE_INTESTINE	Regulation of transforming growth factor beta production →	+0.083	+0.158	<.001	.009	3	4
BONE	Intracellular glucose homeostasis →	+0.064	+0.035	<.001	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 866 associations by consensus.

Retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum by KIAA2012 expression — OVARY

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