F13B

Across TCGA cell cohorts, F13B mutation is significantly associated with the RNA expression of many other genes, with 63 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible F13B-associated genes across cancer lineages are LRIT1, OR4E2, and CCL18. Each is linked with F13B in more than 1 cancer types. Because this analysis shows association rather than direction, both F13B-to-partner and partner-to-F13B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LRIT1 grouped by F13B-low versus F13B-high in LUNG_SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (F13B→partner) and Y-score (partner→F13B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	LRIT1 →	+0.058	+3.736	.001	.007	3	2
LUNG_NSCLC_LUAD	OR4E2 →	+0.028	+3.374	<.001	.002	3	2
LUNG_NSCLC_LUAD	CCL18 →	+0.036	+3.949	<.001	<.001	3	2
LUNG_NSCLC_LUSC	TBL1Y →	+0.053	+4.643	<.001	.008	3	1
LUNG_SCLC	IL27 →	+0.094	+3.817	<.001	.004	3	1
LUNG_SCLC	PAGE3 →	+0.052	+3.817	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 63 associations by consensus.

LRIT1 by F13B expression — LUNG_SCLC

Explore this box plot interactively →