F13B

Across TCGA pan-cancer cohorts, F13B RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of F13B’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where F13B RNA is repressed in tumor relative to normal tissue. In most cancer types F13B is over-expressed in tumor, although a few such as THCA and CHOL show the opposite, repressed pattern.

THCA, CHOL, and UCEC are the cancer types where F13B tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in F13B RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	Female	II,III,IV	−0.017	.009	6	view →
CHOL	Female	All	−6.693	<.001	5	view →
UCEC	All	II,III,IV	+0.024	.016	4	view →
BRCA	All	II,III,IV	+0.020	<.001	4	view →
KIRC	All	All	+0.009	.001	2	view →
LUAD	All	All	+0.008	.009	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

F13B–THCA

Open the THCA breakdown →