F13B

Across TCGA pan-cancer cohorts, F13B RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated F13B data layer compared with 5 for mutation status and 8 for mass-spec protein.

The strongest signal is observed in mesothelioma (MESO), where higher F13B RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated F13B expression acts as an unfavorable survival marker, although some lineages such as LIHC and COAD show a favorable association.

MESO, ACC, and UCEC are the cancer types where F13B RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	DFS	Quartile	All	0.227	0.403	.003	73	view →
ACC	DFS	Quartile	All	0.117	0.541	<.001	63	view →
UCEC	DFS	Tertile	All	0.758	0.865	<.001	52	view →
LIHC	DFS	Tertile	III,IV	0.317	0.087	.006	45	view →
PCPG	OS	Tertile	All	0.873	0.993	<.001	42	view →
COAD	DFS	Tertile	All	0.924	0.506	.010	36	view →
UVM	DFS	Tertile	All	0.079	0.746	<.001	36	view →
ESCA	DFS	Median	All	0.392	0.590	.003	33	view →
LGG	DFS	Quartile	All	0.615	0.778	<.001	32	view →
TGCT	DFS	Tertile	III,IV	0.340	1.000	.010	32	view →
CHOL	OS	Tertile	II,III,IV	0.213	1.000	.004	30	view →
PRAD	DFS	Tertile	All	0.787	0.899	.005	30	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

F13B–MESO (DFS)

Open the MESO breakdown →