OR4E2

associated omics data
Gene

Q-omics provides the consensus-scored OR4E2 profile across patient tissues and cancer cell-line models. OR4E2 expression is associated with patient survival in 8 of 34 cancer types, with the highest sampling consensus in MESO. Additionally, OR4E2 RNA expression shows 6,338 significant gene co-expression associations, with the highest sampling consensus in THYM. Together, these results highlight MESO, and THYM as cancer lineages where OR4E2 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

Survival associations

This table summarizes OR4E2 survival associations across molecular data types. OR4E2 RNA expression shows survival associations in the most cancer types (8), followed by mutation status (2). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
OR4E2 data typeSurvival analysisLineage consensusLineage of highest sampling consensus
RNAKaplan–Meier8MESO (126)view →
MutationKaplan–Meier2SKCM (3)view →
This table ranks reproducible OR4E2 RNA expression–survival associations across cancer types. High OR4E2 expression shows unfavorable associations in MESO, UVM, BRCA, LIHC and STAD, but favorable associations in PAAD. The MESO Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify MESO as the clearest survival context for OR4E2 RNA expression.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
MESOOSTertileIV0.0360.602<.001126view →
UVMOSTertileAll0.1040.858<.00199view →
BRCADFSTertileAll0.1401.000.00136view →
LIHCDFSTertileAll0.1290.557.00227view →
STADDFSTertileAll0.4980.674.00718view →
PAADDFSTertileII,III,IV0.8180.433.03115view →
Pink = unfavorable, green = favorable. all 8 lineages →

OR4E2-MESO (OS)

Kaplan–Meier survival curve for OR4E2 RNA expression in MESO: high vs low expression groups.

Explore this curve interactively →

Cross-omics associations

This table shows molecular features associated with OR4E2 in patient tissues and cancer cell lines. In patient samples, OR4E2 shows the broadest associations at the RNA and protein expression levels, with THYM recurring as the lineage with the largest associated feature set. In cancer cell lines, OR4E2 RNA and mutation anchors are most strongly linked to RNA-expression features, especially in BREAST, while CRISPR and shRNA rows add functional-dependency signals in LUNG_NSCLC_LUSC and BONE.
Associated data typeStrength (# associated data)Lineage of highest associated data
RNA
RNA6,338THYM (2872)view →
Function (RNA)5,907STAD (5168)view →
Mutation
RNA925SKCM (737)view →
Protein (RPPA)9UCEC (6)view →
Associated data typeStrength (# associated data)Lineage of highest associated data
CRISPR
CRISPR1,707BREAST (143)view →
shRNA1,370LUNG_NSCLC_LUSC (166)view →
RNA
RNA3,321BONE (3007)view →
Function (RNA)1,513BONE (1511)view →
shRNA
RNA1,341BLOOD_Leukemia (569)view →
shRNA1,120SKIN (313)view →
Mutation
Mutation1,268LARGE_INTESTINE (956)view →
RNA7LARGE_INTESTINE (4)view →