Across TCGA patient cohorts, OR4E2 mutation is significantly associated with the RNA expression of many other genes, with 925 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible OR4E2-associated genes across cancer lineages are RNA5SP393, SNRPCP18, and OR4K4P. Each is linked with OR4E2 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR4E2-to-partner and partner-to-OR4E2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR4E2→partner) and Y-score (partner→OR4E2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	RNA5SP393 →	+0.509	+2.829	.009	.007	3	3
BRCA	SNRPCP18 →	+0.205	+5.571	<.001	.002	3	2
SKCM	OR4K4P →	+0.006	+3.424	<.001	.009	3	2
HNSC	OR8D4 →	+0.087	+5.124	<.001	.008	3	2
HNSC	RNA5SP250 →	+0.413	+5.505	<.001	.004	3	2
HNSC	RNU6-636P →	+0.753	+5.368	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 925 associations by consensus.

Exploration

OR4E2 survival (RNA) · tumor vs normal (RNA) · all OR4E2 data types