Across TCGA cell cohorts, OR4E2 mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OR4E2-associated genes across cancer lineages are SSX7, TLX3, and REG1B. Each is linked with OR4E2 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR4E2-to-partner and partner-to-OR4E2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR4E2→partner) and Y-score (partner→OR4E2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	SSX7 →	+0.433	+5.285	<.001	.003	3	1
LARGE_INTESTINE	TLX3 →	+0.548	+3.453	<.001	.009	3	1
LARGE_INTESTINE	REG1B →	+2.389	+3.196	<.001	.007	3	1
LARGE_INTESTINE	UBE2QL1 →	+0.282	+3.722	<.001	.007	3	1
CNS	LGALS14 →	+0.868	+4.981	<.001	.008	3	1
LARGE_INTESTINE	KCND3 →	+0.379	+3.519	.001	.007	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

Exploration

OR4E2 survival (RNA) · tumor vs normal (RNA) · all OR4E2 data types