Q-omics provides the consensus-scored DUSP14 profile across patient tissues and cancer cell-line models. DUSP14 expression is associated with patient survival in 28 of 34 cancer types, with the highest sampling consensus in UVM. Among the 18 cancer types available for tumor–normal comparison, DUSP14 is differentially expressed in 12, with the highest sampling consensus in COAD. Additionally, DUSP14 RNA expression shows 19,833 significant gene co-expression associations, with the highest sampling consensus in ACC. Together, these results highlight UVM, COAD, and ACC as cancer lineages where DUSP14 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for DUSP14 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes DUSP14 survival associations across molecular data types. DUSP14 RNA expression shows survival associations in the most cancer types (28), followed by mutation status (3) and mass-spec protein abundance (4). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible DUSP14 RNA expression–survival associations across cancer types. High DUSP14 expression shows unfavorable associations in UVM, MESO, ACC, BLCA, LIHC and KIRP. The UVM Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify UVM as the clearest survival context for DUSP14 RNA expression.
This table summarizes DUSP14 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 12, while mass-spec protein shows differences in 3. The strongest signals are observed in KIRC for RNA and LSCC for protein.
This table ranks reproducible tumor–normal expression differences for DUSP14. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. DUSP14 shows lower tumor expression in THCA and KICH and higher tumor expression in COAD, HNSC, KIRC and KIRP. The COAD box plot shows higher DUSP14 RNA expression in tumor versus normal tissue (log2 FC = +2.276, t-test p < 0.001).
This table shows molecular features associated with DUSP14 in patient tissues and cancer cell lines. In patient samples, DUSP14 shows the broadest associations at the RNA and protein expression levels, with ACC recurring as the lineage with the largest associated feature set. In cancer cell lines, DUSP14 RNA and mutation anchors are most strongly linked to RNA-expression features, especially in PANCREAS, while CRISPR and shRNA rows add functional-dependency signals in URINARY_TRACT and BONE.
