DUSP14

Across TCGA pan-cancer cohorts, DUSP14 RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of DUSP14’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where DUSP14 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types DUSP14 is over-expressed in tumor, although a few such as THCA and KICH show the opposite, repressed pattern.

COAD, HNSC, and KIRC are the cancer types where DUSP14 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in DUSP14 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Female	III,IV	+2.276	<.001	12	view →
HNSC	Male	IV	+1.925	<.001	12	view →
KIRC	Female	All	+1.035	<.001	12	view →
KIRP	All	III,IV	+0.857	<.001	11	view →
THCA	Male	IV	−1.263	<.001	10	view →
KICH	All	II,III,IV	−1.404	<.001	9	view →
BRCA	Female	II,III,IV	−0.447	<.001	8	view →
LUSC	Female	All	+1.186	<.001	6	view →
READ	Male	All	+2.013	.017	5	view →
LUAD	All	II,III,IV	+0.423	.030	3	view →
LIHC	All	All	−0.367	.004	2	view →
STAD	All	IV	+1.976	.016	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

DUSP14–COAD

Open the COAD breakdown →