DUSP14

Across TCGA patient cohorts, DUSP14 mutation is significantly associated with the RNA expression of many other genes, with 75 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible DUSP14-associated genes across cancer lineages are RN7SL185P, NF1P10, and MIR103A1. Each is linked with DUSP14 in more than 2 cancer types. Because this analysis shows association rather than direction, both DUSP14-to-partner and partner-to-DUSP14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL185P grouped by DUSP14-low versus DUSP14-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DUSP14→partner) and Y-score (partner→DUSP14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RN7SL185P →	+0.134	+7.954	<.001	.008	3	3
CESC	NF1P10 →	+0.101	+5.569	.005	.002	3	2
UCEC	MIR103A1 →	+0.199	+4.885	<.001	.002	3	2
HNSC	VCY →	+0.099	+7.954	<.001	.008	3	2
HNSC	MIR668 →	+0.396	+7.954	<.001	.008	3	2
LUSC	MTND4P18 →	+0.109	+5.474	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 75 associations by consensus.

RN7SL185P by DUSP14 expression — HNSC

Explore this box plot interactively →