DUSP14

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, DUSP14 mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DUSP14-associated genes across cancer lineages are CD4+ Tem and Neutrophils. Each is linked with DUSP14 in more than 1 cancer types. Because this analysis shows association rather than direction, both DUSP14-to-partner and partner-to-DUSP14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD4+ Tem grouped by DUSP14-low versus DUSP14-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DUSP14→partner) and Y-score (partner→DUSP14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCCD4+ Tem →+0.020+6.623<.001.01931
UCECNeutrophils →+0.040+2.166<.001.04031
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

CD4+ Tem by DUSP14 expression — HNSC

Box plot of CD4+ Tem in DUSP14-low vs DUSP14-high samples in HNSC.

Explore this box plot interactively →

Exploration