DUSP14

Across TCGA cell cohorts, DUSP14 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,593 significant associations in total. BONE shows the largest number of these associations.

The most reproducible DUSP14-associated GO terms across cancer lineages are Positive regulation of purine nucleotide biosynthetic process, Positive regulation of ATP biosynthetic process, and Positive regulation of nucleotide biosynthetic process. Each is linked with DUSP14 in more than 10 cancer types. Because this analysis shows association rather than direction, both DUSP14-to-partner and partner-to-DUSP14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of purine nucleotide biosynthetic process grouped by DUSP14-low versus DUSP14-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DUSP14→partner) and Y-score (partner→DUSP14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Positive regulation of purine nucleotide biosynthetic process →	+0.175	+0.759	<.001	<.001	3	11
PANCREAS	Positive regulation of ATP biosynthetic process →	+0.175	+0.760	<.001	<.001	3	11
PANCREAS	Positive regulation of nucleotide biosynthetic process →	+0.175	+0.759	<.001	<.001	3	11
BONE	Mitochondrion to lysosome vesicle-mediated transport →	+0.275	+1.418	<.001	<.001	3	9
BONE	Mitochondrion-derived vesicle mediated transport →	+0.275	+1.418	<.001	<.001	3	9
KIDNEY	Vein smooth muscle contraction →	+1.590	+0.796	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,593 associations by consensus.

Positive regulation of purine nucleotide biosynthetic process by DUSP14 expression — PANCREAS

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