Q-omics provides the consensus-scored BAMBI profile across patient tissues and cancer cell-line models. BAMBI expression is associated with patient survival in 25 of 34 cancer types, with the highest sampling consensus in LIHC. Among the 18 cancer types available for tumor–normal comparison, BAMBI is differentially expressed in 14, with the highest sampling consensus in COAD. Additionally, BAMBI RNA expression shows 15,981 significant gene co-expression associations, with the highest sampling consensus in KIRP. Together, these results highlight LIHC, COAD, and KIRP as cancer lineages where BAMBI shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for BAMBI — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes BAMBI survival associations across molecular data types. BAMBI RNA expression shows survival associations in the most cancer types (25), followed by mutation status (6). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible BAMBI RNA expression–survival associations across cancer types. High BAMBI expression shows unfavorable associations in LIHC, LUAD and THCA, but favorable associations in KIRC, UVM and UCEC. The LIHC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify LIHC as the clearest survival context for BAMBI RNA expression.
This table summarizes BAMBI tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 14. The strongest signals are observed in COAD for RNA.
This table ranks reproducible tumor–normal expression differences for BAMBI. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. BAMBI shows lower tumor expression in KICH and KIRC and higher tumor expression in COAD, STAD, ESCA and CHOL. The COAD box plot shows higher BAMBI RNA expression in tumor versus normal tissue (log2 FC = +1.801, t-test p < 0.001).
This table shows molecular features associated with BAMBI in patient tissues and cancer cell lines. In patient samples, BAMBI shows the broadest associations at the RNA and protein expression levels, with KIRP recurring as the lineage with the largest associated feature set. In cancer cell lines, BAMBI RNA and mutation anchors are most strongly linked to RNA-expression features, especially in SOFT_TISSUE, while CRISPR and shRNA rows add functional-dependency signals in CNS and SKIN.
