BAMBI

Across TCGA patient cohorts, BAMBI mutation is significantly associated with the RNA expression of many other genes, with 1,610 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BAMBI-associated genes across cancer lineages are RNU6-1274P, OR12D1, and IGKV2OR2-10. Each is linked with BAMBI in more than 1 cancer types. Because this analysis shows association rather than direction, both BAMBI-to-partner and partner-to-BAMBI results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1274P grouped by BAMBI-low versus BAMBI-high in READ.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BAMBI→partner) and Y-score (partner→BAMBI) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
READ	RNU6-1274P →	+0.547	+5.925	<.001	.002	3	2
READ	OR12D1 →	+0.108	+6.257	<.001	.001	3	2
BLCA	IGKV2OR2-10 →	+0.196	+3.735	<.001	.005	3	2
LUSC	SNORA108 →	+0.388	+6.593	<.001	<.001	3	2
LUSC	SUGT1P4 →	+0.220	+5.578	<.001	.002	3	2
COAD	ARF4P3 →	+0.434	+5.435	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,610 associations by consensus.

RNU6-1274P by BAMBI expression — READ

Explore this box plot interactively →