BAMBI

Across TCGA cell cohorts, BAMBI mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible BAMBI-associated genes across cancer lineages are OR11H6, DEFB119, and USP17L11. Each is linked with BAMBI in more than 1 cancer types. Because this analysis shows association rather than direction, both BAMBI-to-partner and partner-to-BAMBI results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR11H6 grouped by BAMBI-low versus BAMBI-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BAMBI→partner) and Y-score (partner→BAMBI) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	OR11H6 →	+0.025	+5.209	<.001	.005	3	1
BLOOD_Lymphoma	DEFB119 →	+0.156	+6.247	<.001	<.001	3	1
BLOOD_Lymphoma	USP17L11 →	+0.025	+4.867	<.001	.009	3	1
BLOOD_Lymphoma	USP17L20 →	+0.026	+5.209	<.001	.005	3	1
BLOOD_Lymphoma	USP17L18 →	+0.026	+5.209	<.001	.005	3	1
BREAST	OR10K2 →	+0.063	+5.781	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

OR11H6 by BAMBI expression — BLOOD_Lymphoma

Explore this box plot interactively →