Q-omics provides the consensus-scored USP17L18 profile across patient tissues and cancer cell-line models. USP17L18 expression is associated with patient survival in 3 of 34 cancer types, with the highest sampling consensus in KIRC. Additionally, USP17L18 RNA expression shows 1,678 significant gene co-expression associations, with the highest sampling consensus in STAD. Together, these results highlight KIRC, and STAD as cancer lineages where USP17L18 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

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Survival associations

This table summarizes USP17L18 survival associations across molecular data types. USP17L18 RNA expression shows survival associations in the most cancer types (3). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

USP17L18 data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	3	KIRC (144)	view →

This table ranks reproducible USP17L18 RNA expression–survival associations across cancer types. High USP17L18 expression shows unfavorable associations in KIRC, STAD and HNSC. The KIRC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify KIRC as the clearest survival context for USP17L18 RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Tertile	All	0.127	0.881	<.001	144	view →
STAD	DFS	Tertile	II,III,IV	0.219	0.617	.005	36	view →
HNSC	DFS	Tertile	All	0.209	0.710	.032	18	view →

Pink = unfavorable, green = favorable. all 3 lineages →

USP17L18-KIRC (OS)

Kaplan–Meier survival curve for USP17L18 RNA expression in KIRC: high vs low expression groups.

Explore this curve interactively →

Cross-omics associations

This table shows molecular features associated with USP17L18 in patient tissues and cancer cell lines. In patient samples, USP17L18 shows the broadest associations at the RNA and protein expression levels, with STAD recurring as the lineage with the largest associated feature set. In cancer cell lines, USP17L18 RNA and mutation anchors are most strongly linked to RNA-expression features, especially in OESOPHAGUS, while CRISPR and shRNA rows add functional-dependency signals in BLOOD_Leukemia.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
RNA	1,678	STAD (1350)	view →
Protein (mass-spec)	602	GBM (212)	view →

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
RNA	286	OESOPHAGUS (32)	view →
Mutation	154	BLOOD_Leukemia (51)	view →