USP17L18

Across TCGA patient cohorts, USP17L18 RNA expression is significantly associated with the protein abundance of many other proteins, with 602 significant associations in total. GBM shows the largest number of these associations.

The most reproducible USP17L18-associated proteins across cancer lineages are SPTBN1_S2165, TSPYL5, and TPX2_S486. Each is linked with USP17L18 in more than 1 cancer types. Because this analysis shows association rather than direction, both USP17L18-to-partner and partner-to-USP17L18 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, USP17L18 versus SPTBN1_S2165 in PDAC, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (USP17L18→partner) and Y-score (partner→USP17L18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	SPTBN1_S2165 →	+0.521	+0.033	.006	.003	3	2
GBM	TSPYL5 →	+0.534	+0.020	<.001	.001	3	2
LUAD	TPX2_S486 →	-1.233	-0.036	.008	.009	3	1
LUAD	UBE2O_S896 →	-0.681	-0.023	.002	.007	3	1
LUAD	VPS35_S7 →	-0.471	-0.040	.004	.006	3	1
LUAD	WASF2_Y124 →	+0.394	+0.044	.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 602 associations by consensus.

USP17L18 vs SPTBN1_S2165 — PDAC

Explore this scatter interactively →