Across TCGA patient cohorts, ZYG11A mutation is significantly associated with the RNA expression of many other genes, with 3,151 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZYG11A-associated genes across cancer lineages are RNA5SP412, LINC02559, and KRT18P45. Each is linked with ZYG11A in more than 1 cancer types. Because this analysis shows association rather than direction, both ZYG11A-to-partner and partner-to-ZYG11A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZYG11A→partner) and Y-score (partner→ZYG11A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP412 →	+0.431	+1.552	<.001	.007	3	2
CESC	LINC02559 →	+0.749	+4.020	<.001	.009	3	2
CESC	KRT18P45 →	+0.041	+3.266	<.001	.004	3	2
UCEC	LDHAP1 →	+0.094	+1.463	.002	.008	3	2
UCEC	TLE6 →	+0.584	+1.665	.002	.002	3	2
COAD	CXXC1 →	+0.462	+3.375	.009	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,151 associations by consensus.

Exploration

ZYG11A survival (RNA) · tumor vs normal (RNA) · all ZYG11A data types