Q-omics provides the consensus-scored KRT18P45 profile across patient tissues and cancer cell-line models. KRT18P45 expression is associated with patient survival in 15 of 34 cancer types, with the highest sampling consensus in STAD. Among the 18 cancer types available for tumor–normal comparison, KRT18P45 is differentially expressed in 6, with the highest sampling consensus in HNSC. Additionally, KRT18P45 RNA expression shows 5,336 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight STAD, and HNSC as cancer lineages where KRT18P45 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for KRT18P45 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes KRT18P45 survival associations across molecular data types. KRT18P45 RNA expression shows survival associations in the most cancer types (15). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible KRT18P45 RNA expression–survival associations across cancer types. High KRT18P45 expression shows unfavorable associations in STAD, UVM, THCA and CHOL, but favorable associations in COAD and BLCA. The STAD Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .002). Together, the overview and detailed table identify STAD as the clearest survival context for KRT18P45 RNA expression.
This table summarizes KRT18P45 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 6. The strongest signals are observed in HNSC for RNA.
This table ranks reproducible tumor–normal expression differences for KRT18P45. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. KRT18P45 shows lower tumor expression in PAAD and higher tumor expression in HNSC, COAD, PRAD, THCA and STAD. The HNSC box plot shows higher KRT18P45 RNA expression in tumor versus normal tissue (log2 FC = +0.038, t-test p = .012).
This table shows molecular features associated with KRT18P45 in patient tissues and cancer cell lines. In patient samples, KRT18P45 shows the broadest associations at the RNA and protein expression levels, with STAD recurring as the lineage with the largest associated feature set.
