KRT18P45

Across TCGA pan-cancer cohorts, KRT18P45 RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated KRT18P45 data layer.

The strongest signal is observed in stomach adenocarcinoma (STAD), where higher KRT18P45 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated KRT18P45 expression acts as an unfavorable survival marker, although some lineages such as COAD and BLCA show a favorable association.

STAD, UVM, and COAD are the cancer types where KRT18P45 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
STAD	DFS	Median	All	0.593	0.807	.002	54	view →
UVM	OS	Tertile	All	0.136	0.919	<.001	45	view →
COAD	OS	Tertile	IV	0.878	0.435	.003	42	view →
BLCA	OS	Tertile	All	0.681	0.244	.003	36	view →
CHOL	DFS	Tertile	II,III,IV	0.116	0.420	.025	36	view →
THCA	OS	Tertile	III,IV	0.645	0.962	.004	36	view →
MESO	DFS	Quartile	II,III,IV	0.172	0.296	.006	22	view →
READ	DFS	Tertile	IV	0.330	0.708	.009	18	view →
PAAD	OS	Tertile	III,IV	0.558	0.924	.014	15	view →
LGG	DFS	Tertile	All	0.600	0.861	<.001	15	view →
KIRC	DFS	Tertile	IV	0.173	0.363	.031	12	view →
ESCA	DFS	Quartile	III,IV	0.255	0.449	.008	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

KRT18P45–STAD (DFS)

Open the STAD breakdown →