Q-omics provides the consensus-scored LDHAP1 profile across patient tissues and cancer cell-line models. LDHAP1 expression is associated with patient survival in 13 of 34 cancer types, with the highest sampling consensus in KIRC. Among the 18 cancer types available for tumor–normal comparison, LDHAP1 is differentially expressed in 8, with the highest sampling consensus in LUAD. Additionally, LDHAP1 RNA expression shows 6,013 significant pathway-activity associations, with the highest sampling consensus in UCEC. Together, these results highlight KIRC, LUAD, and UCEC as cancer lineages where LDHAP1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for LDHAP1 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes LDHAP1 survival associations across molecular data types. LDHAP1 RNA expression shows survival associations in the most cancer types (13). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible LDHAP1 RNA expression–survival associations across cancer types. High LDHAP1 expression shows unfavorable associations in STAD, HNSC, KICH, UCS and LUAD, but favorable associations in KIRC. The KIRC Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p < 0.001). Together, the overview and detailed table identify KIRC as the clearest survival context for LDHAP1 RNA expression.
This table summarizes LDHAP1 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 8. The strongest signals are observed in LUAD for RNA.
This table ranks reproducible tumor–normal expression differences for LDHAP1. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. LDHAP1 shows higher tumor expression in LUAD, KIRC, BRCA, COAD, HNSC and UCEC. The LUAD box plot shows higher LDHAP1 RNA expression in tumor versus normal tissue (log2 FC = +0.114, t-test p < 0.001).
This table shows molecular features associated with LDHAP1 in patient tissues and cancer cell lines. In patient samples, LDHAP1 shows the broadest associations at the RNA and protein expression levels, with UCEC recurring as the lineage with the largest associated feature set.
