LDHAP1

Across TCGA pan-cancer cohorts, LDHAP1 RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of LDHAP1’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where LDHAP1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LDHAP1 is over-expressed in tumor, although a few such as KICH show the opposite, repressed pattern.

LUAD, KIRC, and BRCA are the cancer types where LDHAP1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LDHAP1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	All	II,III,IV	+0.114	<.001	9	view →
KIRC	Male	All	+0.062	<.001	8	view →
BRCA	All	II,III,IV	+0.028	.001	6	view →
COAD	All	II,III,IV	+0.171	.001	5	view →
HNSC	Male	All	+0.093	.016	4	view →
UCEC	All	All	+0.132	.005	2	view →
KICH	Female	III,IV	−0.053	.039	1	view →
LUSC	All	All	+0.035	.032	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 8 strongest of 8 lineages.

LDHAP1–LUAD

Open the LUAD breakdown →