Q-omics provides the consensus-scored ZNF98 profile across patient tissues and cancer cell-line models. ZNF98 expression is associated with patient survival in 18 of 34 cancer types, with the highest sampling consensus in UVM. Among the 18 cancer types available for tumor–normal comparison, ZNF98 is differentially expressed in 12, with the highest sampling consensus in KIRC. Additionally, ZNF98 RNA expression shows 16,077 significant gene co-expression associations, with the highest sampling consensus in THYM. Together, these results highlight UVM, KIRC, and THYM as cancer lineages where ZNF98 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for ZNF98 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes ZNF98 survival associations across molecular data types. ZNF98 RNA expression shows survival associations in the most cancer types (18), followed by mutation status (5). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible ZNF98 RNA expression–survival associations across cancer types. High ZNF98 expression shows unfavorable associations in CESC and READ, but favorable associations in UVM, HNSC, LGG and MESO. The UVM Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p < 0.001). Together, the overview and detailed table identify UVM as the clearest survival context for ZNF98 RNA expression.
This table summarizes ZNF98 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 12. The strongest signals are observed in KIRC for RNA.
This table ranks reproducible tumor–normal expression differences for ZNF98. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. ZNF98 shows lower tumor expression in KIRC, THCA, COAD, KIRP, KICH and LUSC. The KIRC box plot shows higher ZNF98 RNA expression in normal versus tumor tissue (log2 FC = −0.977, t-test p < 0.001).
This table shows molecular features associated with ZNF98 in patient tissues and cancer cell lines. In patient samples, ZNF98 shows the broadest associations at the RNA and protein expression levels, with THYM recurring as the lineage with the largest associated feature set. In cancer cell lines, ZNF98 RNA and mutation anchors are most strongly linked to RNA-expression features, especially in CNS, while CRISPR and shRNA rows add functional-dependency signals in BLOOD_Leukemia and LUNG_NSCLC_LUAD.
