Across TCGA patient cohorts, ZNF98 mutation is significantly associated with the total protein of many other genes, with 69 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF98-associated genes across cancer lineages are Caveolin-1, FASN, and PREX1. Each is linked with ZNF98 in more than 4 cancer types. Because this analysis shows association rather than direction, both ZNF98-to-partner and partner-to-ZNF98 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF98→partner) and Y-score (partner→ZNF98) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Caveolin-1 →	-0.436	-2.459	.049	.018	3	5
COAD	FASN →	+0.581	+3.000	<.001	.034	3	3
SKCM	PREX1 →	-0.213	-2.000	.048	.027	3	3
UCEC	ATM →	-0.453	-2.794	.001	.002	3	3
UCEC	Caspase-7-cleavedD198 →	+0.530	+1.502	.003	.025	3	3
STAD	Cyclin-D1 →	-0.465	-3.000	.028	.036	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 69 associations by consensus.

Exploration

ZNF98 survival (RNA) · tumor vs normal (RNA) · all ZNF98 data types