Across TCGA patient cohorts, ZNF98 mutation is significantly associated with the RNA expression of many other genes, with 3,984 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF98-associated genes across cancer lineages are FOXRED1, KIF2C, and CHEK1. Each is linked with ZNF98 in more than 4 cancer types. Because this analysis shows association rather than direction, both ZNF98-to-partner and partner-to-ZNF98 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF98→partner) and Y-score (partner→ZNF98) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FOXRED1 →	+0.380	+2.480	<.001	<.001	3	5
UCEC	KIF2C →	+0.589	+1.546	.001	.001	3	5
UCEC	CHEK1 →	+0.594	+1.860	<.001	<.001	3	5
UCEC	POLD1 →	+0.430	+1.568	.002	.001	3	5
UCEC	UQCRH →	+0.658	+1.557	.003	.001	3	4
SKCM	TRAIP →	+0.387	+1.305	<.001	.004	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,984 associations by consensus.

Exploration

ZNF98 survival (RNA) · tumor vs normal (RNA) · all ZNF98 data types