Q-omics provides the consensus-scored TRAIP profile across patient tissues and cancer cell-line models. TRAIP expression is associated with patient survival in 28 of 34 cancer types, with the highest sampling consensus in KIRC. Among the 18 cancer types available for tumor–normal comparison, TRAIP is differentially expressed in 15, with the highest sampling consensus in BLCA. Additionally, TRAIP RNA expression shows 25,604 significant protein co-abundance associations, with the highest sampling consensus in LSCC. Together, these results highlight KIRC, BLCA, and LSCC as cancer lineages where TRAIP shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for TRAIP — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes TRAIP survival associations across molecular data types. TRAIP RNA expression shows survival associations in the most cancer types (28), followed by mutation status (2). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible TRAIP RNA expression–survival associations across cancer types. High TRAIP expression shows unfavorable associations in KIRC, ACC, KICH, LIHC, MESO and SKCM. The KIRC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify KIRC as the clearest survival context for TRAIP RNA expression.
This table summarizes TRAIP tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 15. The strongest signals are observed in BLCA for RNA.
This table ranks reproducible tumor–normal expression differences for TRAIP. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. TRAIP shows higher tumor expression in BLCA, COAD, LUAD, KIRP, HNSC and LIHC. The BLCA box plot shows higher TRAIP RNA expression in tumor versus normal tissue (log2 FC = +1.751, t-test p < 0.001).
This table shows molecular features associated with TRAIP in patient tissues and cancer cell lines. In patient samples, TRAIP shows the broadest associations at the RNA and protein expression levels, with LSCC recurring as the lineage with the largest associated feature set. In cancer cell lines, TRAIP RNA and mutation anchors are most strongly linked to RNA-expression features, especially in BREAST, while CRISPR and shRNA rows add functional-dependency signals in CNS and BLOOD_Leukemia.
