Across TCGA cell cohorts, TRAIP mutation is significantly associated with the RNA expression of many other genes, with 33 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TRAIP-associated genes across cancer lineages are VSIG4, TBC1D3, and GML. Each is linked with TRAIP in more than 1 cancer types. Because this analysis shows association rather than direction, both TRAIP-to-partner and partner-to-TRAIP results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRAIP→partner) and Y-score (partner→TRAIP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	VSIG4 →	+0.023	+5.029	<.001	.006	3	1
LARGE_INTESTINE	TBC1D3 →	+0.080	+4.273	<.001	.006	3	1
BLOOD_Leukemia	GML →	+0.091	+4.567	<.001	.001	3	1
BLOOD_Leukemia	PHOX2B →	+0.024	+4.365	<.001	.002	3	1
BLOOD_Leukemia	IL17F →	+0.049	+3.855	<.001	.007	3	1
BLOOD_Leukemia	MMP27 →	+0.015	+4.384	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 33 associations by consensus.

Exploration

TRAIP survival (RNA) · tumor vs normal (RNA) · all TRAIP data types