TRAIP

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, TRAIP mutation is significantly associated with the total protein of many other genes, with 34 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TRAIP-associated genes across cancer lineages are PCNA, eIF4G, and ATM. Each is linked with TRAIP in more than 2 cancer types. Because this analysis shows association rather than direction, both TRAIP-to-partner and partner-to-TRAIP results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRAIP→partner) and Y-score (partner→TRAIP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECPCNA →+0.336+3.459<.001.00533
UCECeIF4G →+0.261+1.678.028.02332
UCECATM →-0.605-2.087<.001.00532
UCECCaspase-7-cleavedD198 →+0.565+1.894.013.03032
UCECCaspase-8 →-0.306-2.880.001.00132
UCECC-Raf →+0.150+3.169.006.01832
Each partner links to its Q-omics profile. Showing the 6 strongest of 34 associations by consensus.

Exploration