Q-omics provides the consensus-scored ZNF271P profile across patient tissues and cancer cell-line models. ZNF271P expression is associated with patient survival in 23 of 34 cancer types, with the highest sampling consensus in ACC. Among the 18 cancer types available for tumor–normal comparison, ZNF271P is differentially expressed in 9, with the highest sampling consensus in THCA. Additionally, ZNF271P RNA expression shows 20,426 significant gene co-expression associations, with the highest sampling consensus in UVM. Together, these results highlight ACC, THCA, and UVM as cancer lineages where ZNF271P shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for ZNF271P — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes ZNF271P survival associations across molecular data types. ZNF271P RNA expression shows survival associations in the most cancer types (23), followed by mutation status (5). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible ZNF271P RNA expression–survival associations across cancer types. High ZNF271P expression shows unfavorable associations in ACC, BLCA, LIHC and UVM, but favorable associations in OV and KIRC. The ACC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify ACC as the clearest survival context for ZNF271P RNA expression.
This table summarizes ZNF271P tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 9. The strongest signals are observed in THCA for RNA.
This table ranks reproducible tumor–normal expression differences for ZNF271P. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. ZNF271P shows lower tumor expression in THCA, KICH, COAD, KIRP and KIRC and higher tumor expression in LIHC. The THCA box plot shows higher ZNF271P RNA expression in normal versus tumor tissue (log2 FC = −1.316, t-test p < 0.001).
This table shows molecular features associated with ZNF271P in patient tissues and cancer cell lines. In patient samples, ZNF271P shows the broadest associations at the RNA and protein expression levels, with UVM recurring as the lineage with the largest associated feature set. In cancer cell lines, ZNF271P RNA and mutation anchors are most strongly linked to RNA-expression features, especially in NCI60_ALL.
