ZNF271P

Across TCGA patient cohorts, ZNF271P mutation is significantly associated with the total protein of many other genes, with 43 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF271P-associated genes across cancer lineages are 4E-BP1, eIF4E, and mTOR_pS2448. Each is linked with ZNF271P in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF271P-to-partner and partner-to-ZNF271P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, 4E-BP1 grouped by ZNF271P-low versus ZNF271P-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF271P→partner) and Y-score (partner→ZNF271P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	4E-BP1 →	+0.383	+3.807	<.001	<.001	3	2
UCEC	eIF4E →	+0.238	+2.874	.001	<.001	3	2
UCEC	mTOR_pS2448 →	-0.129	-1.787	.014	.026	3	2
UCEC	ASNS →	+0.404	+1.906	.001	.015	3	2
UCEC	Caspase-7-cleavedD198 →	+0.656	+1.505	.001	.034	3	2
UCEC	14-3-3_beta →	-0.092	-3.432	.009	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 43 associations by consensus.

4E-BP1 by ZNF271P expression — UCEC

Explore this box plot interactively →