ZHX1-C8orf76

Across TCGA patient cohorts, ZHX1-C8orf76 mutation is significantly associated with the RNA expression of many other genes, with 706 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZHX1-C8orf76-associated genes across cancer lineages are IGHD1-1, TAS2R7, and ACTR3P3. Each is linked with ZHX1-C8orf76 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZHX1-C8orf76-to-partner and partner-to-ZHX1-C8orf76 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IGHD1-1 grouped by ZHX1-C8orf76-low versus ZHX1-C8orf76-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZHX1-C8orf76→partner) and Y-score (partner→ZHX1-C8orf76) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	IGHD1-1 →	+0.592	+3.750	<.001	.002	3	2
COAD	TAS2R7 →	+0.060	+6.721	.007	<.001	3	2
LUAD	ACTR3P3 →	+0.060	+5.798	<.001	.003	3	2
COAD	SPANXD →	+0.209	+6.003	.005	.002	3	1
COAD	RNU6-147P →	+0.449	+5.212	.005	.007	3	1
COAD	H3P21 →	+0.151	+6.547	.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 706 associations by consensus.

IGHD1-1 by ZHX1-C8orf76 expression — UCEC

Explore this box plot interactively →