Q-omics provides the consensus-scored ACTR3P3 profile across patient tissues and cancer cell-line models. ACTR3P3 expression is associated with patient survival in 11 of 34 cancer types, with the highest sampling consensus in COAD. Additionally, ACTR3P3 RNA expression shows 6,123 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight COAD, and STAD as cancer lineages where ACTR3P3 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

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Survival associations

This table summarizes ACTR3P3 survival associations across molecular data types. ACTR3P3 RNA expression shows survival associations in the most cancer types (11). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

ACTR3P3 data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	11	COAD (48)	view →

This table ranks reproducible ACTR3P3 RNA expression–survival associations across cancer types. High ACTR3P3 expression shows unfavorable associations in COAD, BLCA, TGCT, UCEC and LUAD, but favorable associations in ESCA. The COAD Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify COAD as the clearest survival context for ACTR3P3 RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	OS	Tertile	III,IV	0.208	0.799	<.001	48	view →
ESCA	OS	Quartile	III,IV	0.658	0.350	.015	46	view →
BLCA	OS	Tertile	IV	0.051	0.600	<.001	36	view →
TGCT	OS	Tertile	All	0.069	0.968	<.001	36	view →
UCEC	OS	Tertile	All	0.590	0.693	.011	18	view →
LUAD	OS	Tertile	III,IV	0.223	0.677	.006	18	view →

Pink = unfavorable, green = favorable. all 11 lineages →

ACTR3P3-COAD (OS)

Kaplan–Meier survival curve for ACTR3P3 RNA expression in COAD: high vs low expression groups.

Explore this curve interactively →

Cross-omics associations

This table shows molecular features associated with ACTR3P3 in patient tissues and cancer cell lines. In patient samples, ACTR3P3 shows the broadest associations at the RNA and protein expression levels, with STAD recurring as the lineage with the largest associated feature set.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
Function (RNA)	6,123	STAD (5751)	view →
Protein (mass-spec)	1,960	OV (371)	view →