ACTR3P3

Across TCGA pan-cancer cohorts, ACTR3P3 RNA is linked to patient survival in 11 of 34 cancer types, making it the most broadly survival-associated ACTR3P3 data layer.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher ACTR3P3 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated ACTR3P3 expression acts as an unfavorable survival marker, although some lineages such as ESCA and STAD show a favorable association.

COAD, ESCA, and BLCA are the cancer types where ACTR3P3 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	OS	Tertile	III,IV	0.208	0.799	<.001	48	view →
ESCA	OS	Quartile	III,IV	0.658	0.350	.015	46	view →
BLCA	OS	Tertile	IV	0.051	0.600	<.001	36	view →
TGCT	OS	Tertile	All	0.069	0.968	<.001	36	view →
LUAD	OS	Tertile	III,IV	0.223	0.677	.006	18	view →
KIRC	DFS	Tertile	IV	0.167	0.536	.021	18	view →
SARC	OS	Tertile	All	0.574	0.876	.001	18	view →
UCEC	OS	Tertile	All	0.590	0.693	.011	18	view →
STAD	OS	Quartile	IV	0.860	0.282	.019	9	view →
THCA	DFS	Tertile	All	0.051	0.811	<.001	9	view →
LUSC	DFS	Tertile	III,IV	0.388	0.673	.046	3	view →

Pink = unfavorable, green = favorable. Showing the 11 strongest of 11 lineages.

ACTR3P3–COAD (OS)

Open the COAD breakdown →