ACTR3P3

Across TCGA patient cohorts, ACTR3P3 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,123 significant associations in total. STAD shows the largest number of these associations.

The most reproducible ACTR3P3-associated GO terms across cancer lineages are Positive regulation of DNA-templated transcription initiation, Cellular respiration, and Monosaccharide metabolic process. Each is linked with ACTR3P3 in more than 9 cancer types. Because this analysis shows association rather than direction, both ACTR3P3-to-partner and partner-to-ACTR3P3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of DNA-templated transcription initiation grouped by ACTR3P3-low versus ACTR3P3-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ACTR3P3→partner) and Y-score (partner→ACTR3P3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Positive regulation of DNA-templated transcription initiation →	+0.069	+0.076	<.001	<.001	3	10
STAD	Cellular respiration →	+0.075	+0.082	<.001	<.001	3	9
STAD	Monosaccharide metabolic process →	+0.063	+0.081	<.001	<.001	3	8
STAD	Maturation of SSU-rRNA →	+0.077	+0.077	<.001	<.001	3	8
STAD	Negative regulation of protein ubiquitination →	+0.068	+0.082	<.001	<.001	3	8
STAD	DNA integrity checkpoint signaling →	+0.076	+0.087	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,123 associations by consensus.

Positive regulation of DNA-templated transcription initiation by ACTR3P3 expression — STAD

Explore this box plot interactively →