Q-omics provides the consensus-scored TUNAR profile across patient tissues and cancer cell-line models. TUNAR expression is associated with patient survival in 21 of 34 cancer types, with the highest sampling consensus in KIRP. Among the 18 cancer types available for tumor–normal comparison, TUNAR is differentially expressed in 8, with the highest sampling consensus in KIRC. Additionally, TUNAR RNA expression shows 11,084 significant gene co-expression associations, with the highest sampling consensus in TGCT. Together, these results highlight KIRP, KIRC, and TGCT as cancer lineages where TUNAR shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for TUNAR — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes TUNAR survival associations across molecular data types. TUNAR RNA expression shows survival associations in the most cancer types (21). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible TUNAR RNA expression–survival associations across cancer types. High TUNAR expression shows unfavorable associations in ACC, but favorable associations in KIRP, KIRC, BRCA, SKCM and LGG. The KIRP Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p = .002). Together, the overview and detailed table identify KIRP as the clearest survival context for TUNAR RNA expression.
This table summarizes TUNAR tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 8. The strongest signals are observed in KIRC for RNA.
This table ranks reproducible tumor–normal expression differences for TUNAR. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. TUNAR shows lower tumor expression in KIRC, KICH, UCEC and BRCA and higher tumor expression in KIRP and THCA. The KIRC box plot shows higher TUNAR RNA expression in normal versus tumor tissue (log2 FC = −0.788, t-test p < 0.001).
This table shows molecular features associated with TUNAR in patient tissues and cancer cell lines. In patient samples, TUNAR shows the broadest associations at the RNA and protein expression levels, with TGCT recurring as the lineage with the largest associated feature set.
