TUNAR

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, TUNAR RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated TUNAR data layer.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher TUNAR RNA is associated with better overall survival. In most high-consensus cancer types, elevated TUNAR expression acts as an unfavorable survival marker, although some lineages such as KIRP and KIRC show a favorable association.

KIRP, KIRC, and BRCA are the cancer types where TUNAR RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
KIRPOSTertileAll0.9720.875.00252view →
KIRCDFSTertileAll0.7670.585<.00149view →
BRCADFSMedianAll0.5680.485<.00145view →
ACCDFSTertileIII,IV0.2550.680.00127view →
SKCMDFSMedianIII,IV0.7160.507.00223view →
LGGDFSMedianAll0.4870.329.00123view →
LUADOSTertileAll0.6610.292.02719view →
THYMDFSTertileII,III,IV1.0000.505.00916view →
PAADDFSQuartileAll0.5580.239.00315view →
UVMOSQuartileIII,IV0.3840.933.01815view →
STADDFSMedianIII,IV0.5930.260.02115view →
BLCAOSQuartileIV0.1160.304.00110view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

TUNAR–KIRP (OS)

Kaplan–Meier survival curve for TUNAR RNA-high vs -low samples in KIRP.

Open the KIRP breakdown →

Exploration