TRIM51HP

Across TCGA patient cohorts, TRIM51HP mutation is significantly associated with the RNA expression of many other genes, with 1,989 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TRIM51HP-associated genes across cancer lineages are LINC01670, RNA5SP463, and SRRT. Each is linked with TRIM51HP in more than 2 cancer types. Because this analysis shows association rather than direction, both TRIM51HP-to-partner and partner-to-TRIM51HP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC01670 grouped by TRIM51HP-low versus TRIM51HP-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIM51HP→partner) and Y-score (partner→TRIM51HP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	LINC01670 →	+0.077	+2.088	<.001	.003	3	3
LUSC	RNA5SP463 →	+0.174	+2.452	.002	.001	3	3
LUAD	SRRT →	+0.426	+2.662	<.001	<.001	3	3
SKCM	TRAIP →	+0.578	+2.751	<.001	.002	3	3
SKCM	TEDC1 →	+0.680	+3.028	<.001	<.001	3	3
UCEC	NELFB →	+0.524	+2.637	.001	.005	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,989 associations by consensus.

LINC01670 by TRIM51HP expression — UCEC

Explore this box plot interactively →