TRIM51HP

Across TCGA pan-cancer cohorts, TRIM51HP RNA is linked to patient survival in 14 of 34 cancer types, making it the most broadly survival-associated TRIM51HP data layer compared with 5 for mutation status.

The strongest signal is observed in lymphoid neoplasm diffuse large b-cell lymphoma (DLBC), where higher TRIM51HP RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated TRIM51HP expression acts as an unfavorable survival marker.

DLBC, BLCA, and UVM are the cancer types where TRIM51HP RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
DLBC	DFS	Tertile	IV	0.125	0.744	<.001	126	view →
BLCA	DFS	Tertile	All	0.094	0.594	.001	81	view →
UVM	OS	Tertile	All	0.517	0.812	.006	54	view →
UCS	DFS	Tertile	III,IV	0.146	0.462	.002	48	view →
LIHC	OS	Tertile	II,III,IV	0.051	0.696	<.001	36	view →
HNSC	OS	Tertile	IV	0.058	0.642	.001	36	view →
BRCA	OS	Tertile	II,III,IV	0.212	0.572	.005	18	view →
KIRC	DFS	Tertile	IV	0.114	0.640	.002	18	view →
THYM	OS	Tertile	All	0.767	0.976	.013	18	view →
LGG	OS	Tertile	All	0.184	0.534	.001	18	view →
PCPG	DFS	Tertile	All	0.070	0.936	<.001	18	view →
LAML	DFS	Tertile	All	0.028	0.583	.001	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 14 lineages.

TRIM51HP–DLBC (DFS)

Open the DLBC breakdown →