TNFSF18

Across TCGA cell cohorts, TNFSF18 mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TNFSF18-associated genes across cancer lineages are TRIM49D2, IL2, and FAM81B. Each is linked with TNFSF18 in more than 1 cancer types. Because this analysis shows association rather than direction, both TNFSF18-to-partner and partner-to-TNFSF18 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TRIM49D2 grouped by TNFSF18-low versus TNFSF18-high in STOMACH.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TNFSF18→partner) and Y-score (partner→TNFSF18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	TRIM49D2 →	+0.040	+5.285	<.001	.003	3	1
LARGE_INTESTINE	IL2 →	+0.034	+3.700	<.001	.009	3	1
LARGE_INTESTINE	FAM81B →	+0.305	+3.333	<.001	.009	3	1
LARGE_INTESTINE	FMR1NB →	+0.213	+4.038	<.001	.001	3	1
LARGE_INTESTINE	FSCB →	+0.002	+3.700	<.001	.009	3	1
LARGE_INTESTINE	TECRL →	+0.012	+3.562	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

TRIM49D2 by TNFSF18 expression — STOMACH

Explore this box plot interactively →