Q-omics provides the consensus-scored TRIM49D2 profile across patient tissues and cancer cell-line models. TRIM49D2 expression is associated with patient survival in 3 of 34 cancer types, with the highest sampling consensus in KIRC. Additionally, TRIM49D2 RNA expression shows 5,027 significant gene co-expression associations, with the highest sampling consensus in LUSC. Together, these results highlight KIRC, and LUSC as cancer lineages where TRIM49D2 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

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Survival associations

This table summarizes TRIM49D2 survival associations across molecular data types. TRIM49D2 RNA expression shows survival associations in the most cancer types (3). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

TRIM49D2 data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	3	KIRC (108)	view →

This table ranks reproducible TRIM49D2 RNA expression–survival associations across cancer types. High TRIM49D2 expression shows unfavorable associations in KIRC, SKCM and LGG. The KIRC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify KIRC as the clearest survival context for TRIM49D2 RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Tertile	II,III,IV	0.127	0.806	<.001	108	view →
SKCM	DFS	Tertile	III,IV	0.043	0.597	<.001	45	view →
LGG	OS	Tertile	All	0.101	0.909	<.001	36	view →

Pink = unfavorable, green = favorable. all 3 lineages →

TRIM49D2-KIRC (OS)

Kaplan–Meier survival curve for TRIM49D2 RNA expression in KIRC: high vs low expression groups.

Explore this curve interactively →

Cross-omics associations

This table shows molecular features associated with TRIM49D2 in patient tissues and cancer cell lines. In patient samples, TRIM49D2 shows the broadest associations at the RNA and protein expression levels, with LUSC recurring as the lineage with the largest associated feature set. In cancer cell lines, TRIM49D2 RNA and mutation anchors are most strongly linked to RNA-expression features, especially in BONE, while CRISPR and shRNA rows add functional-dependency signals in BLOOD_Myeloma and LUNG_NSCLC_LUSC.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
RNA	5,027	LUSC (4419)	view →
Function (RNA)	828	STAD (809)	view →

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼shRNA
RNA	2,065	BONE (294)	view →
shRNA	1,857	BLOOD_Myeloma (193)	view →
▼RNA
RNA	845	LUNG_NSCLC_LUSC (244)	view →
CRISPR	227	LUNG_NSCLC_LUAD (93)	view →