TRIM49D2

Across TCGA patient cohorts, TRIM49D2 RNA expression is significantly associated with the go_rna of many other GO terms, with 828 significant associations in total. STAD shows the largest number of these associations.

The most reproducible TRIM49D2-associated GO terms across cancer lineages are Modification of synaptic structure, Mitotic nuclear membrane organization, and Regulation of proton transport. Each is linked with TRIM49D2 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRIM49D2-to-partner and partner-to-TRIM49D2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Modification of synaptic structure grouped by TRIM49D2-low versus TRIM49D2-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIM49D2→partner) and Y-score (partner→TRIM49D2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Modification of synaptic structure →	+0.075	+0.002	<.001	<.001	3	1
STAD	Mitotic nuclear membrane organization →	+0.082	+0.002	.001	<.001	3	1
STAD	Regulation of proton transport →	+0.081	+0.002	<.001	<.001	3	1
STAD	Response to X-ray →	+0.065	+0.002	.002	<.001	3	1
STAD	Response to ionizing radiation →	+0.073	+0.002	.003	<.001	3	1
STAD	Exit from mitosis →	+0.068	+0.002	.004	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 828 associations by consensus.

Modification of synaptic structure by TRIM49D2 expression — STAD

Explore this box plot interactively →