Q-omics provides the consensus-scored TEX11 profile across patient tissues and cancer cell-line models. TEX11 expression is associated with patient survival in 22 of 34 cancer types, with the highest sampling consensus in COAD. Among the 18 cancer types available for tumor–normal comparison, TEX11 is differentially expressed in 13, with the highest sampling consensus in KIRC. Additionally, TEX11 RNA expression shows 14,474 significant gene co-expression associations, with the highest sampling consensus in UVM. Together, these results highlight COAD, KIRC, and UVM as cancer lineages where TEX11 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for TEX11 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes TEX11 survival associations across molecular data types. TEX11 RNA expression shows survival associations in the most cancer types (22), followed by mutation status (4) and mass-spec protein abundance (1). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible TEX11 RNA expression–survival associations across cancer types. High TEX11 expression shows unfavorable associations in UVM, but favorable associations in COAD, HNSC, KIRC, ESCA and DLBC. The COAD Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p < 0.001). Together, the overview and detailed table identify COAD as the clearest survival context for TEX11 RNA expression.
This table summarizes TEX11 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 13. The strongest signals are observed in KIRC for RNA.
This table ranks reproducible tumor–normal expression differences for TEX11. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. TEX11 shows lower tumor expression in COAD, READ and KICH and higher tumor expression in KIRC, HNSC and LUAD. The KIRC box plot shows higher TEX11 RNA expression in tumor versus normal tissue (log2 FC = +2.358, t-test p < 0.001).
This table shows molecular features associated with TEX11 in patient tissues and cancer cell lines. In patient samples, TEX11 shows the broadest associations at the RNA and protein expression levels, with UVM recurring as the lineage with the largest associated feature set. In cancer cell lines, TEX11 RNA and mutation anchors are most strongly linked to RNA-expression features, especially in OESOPHAGUS, while CRISPR and shRNA rows add functional-dependency signals in KIDNEY and LARGE_INTESTINE.
