TEX11

Across TCGA patient cohorts, TEX11 mutation is significantly associated with the RNA expression of many other genes, with 2,977 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TEX11-associated genes across cancer lineages are MTCO3P8, AARS1, and RORA-AS2. Each is linked with TEX11 in more than 2 cancer types. Because this analysis shows association rather than direction, both TEX11-to-partner and partner-to-TEX11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MTCO3P8 grouped by TEX11-low versus TEX11-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TEX11→partner) and Y-score (partner→TEX11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	MTCO3P8 →	+0.026	+1.747	.009	.004	3	3
UCEC	AARS1 →	+0.421	+1.617	<.001	.001	3	3
HNSC	RORA-AS2 →	+0.102	+5.069	<.001	.008	3	3
HNSC	MIR4438 →	+0.521	+7.623	<.001	<.001	3	3
UCEC	BCCIP →	+0.308	+2.052	.006	.004	3	3
UCEC	YARS1 →	+0.462	+1.860	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,977 associations by consensus.

MTCO3P8 by TEX11 expression — SKCM

Explore this box plot interactively →