TEX11

Across TCGA cell cohorts, TEX11 mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TEX11-associated genes across cancer lineages are OR13C7, OR2L8, and KLHDC7B. Each is linked with TEX11 in more than 1 cancer types. Because this analysis shows association rather than direction, both TEX11-to-partner and partner-to-TEX11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR13C7 grouped by TEX11-low versus TEX11-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TEX11→partner) and Y-score (partner→TEX11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	OR13C7 →	+0.038	+5.369	<.001	.004	3	1
SOFT_TISSUE	OR2L8 →	+0.039	+5.369	<.001	.004	3	1
LARGE_INTESTINE	KLHDC7B →	+0.976	+3.485	<.001	.004	3	1
LARGE_INTESTINE	RASGEF1C →	+0.307	+3.404	<.001	.006	3	1
LARGE_INTESTINE	OR2C1 →	+0.132	+3.578	<.001	.006	3	1
LARGE_INTESTINE	IQCF6 →	+0.194	+3.297	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

OR13C7 by TEX11 expression — SOFT_TISSUE

Explore this box plot interactively →