Across TCGA patient cohorts, SYCE1L mutation is significantly associated with the RNA expression of many other genes, with 23 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SYCE1L-associated genes across cancer lineages are NTAN1P1, RN7SL248P, and MIR5688. Each is linked with SYCE1L in more than 1 cancer types. Because this analysis shows association rather than direction, both SYCE1L-to-partner and partner-to-SYCE1L results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SYCE1L→partner) and Y-score (partner→SYCE1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	NTAN1P1 →	+0.205	+5.937	.002	.002	3	1
UCEC	RN7SL248P →	+0.299	+6.722	<.001	<.001	3	1
UCEC	MIR5688 →	+0.746	+5.358	<.001	.006	3	1
UCEC	MIR4511 →	+0.791	+5.242	<.001	.007	3	1
UCEC	MIR5691 →	+1.346	+5.694	<.001	.003	3	1
UCEC	RNU4-58P →	+0.497	+5.133	.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 23 associations by consensus.

Exploration

SYCE1L survival (RNA) · tumor vs normal (RNA) · all SYCE1L data types