SAMD4B

Across TCGA patient cohorts, SAMD4B mutation is significantly associated with the RNA expression of many other genes, with 1,065 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SAMD4B-associated genes across cancer lineages are NCOR1P1, MTCO2P9, and C4BPAP1. Each is linked with SAMD4B in more than 2 cancer types. Because this analysis shows association rather than direction, both SAMD4B-to-partner and partner-to-SAMD4B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NCOR1P1 grouped by SAMD4B-low versus SAMD4B-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SAMD4B→partner) and Y-score (partner→SAMD4B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	NCOR1P1 →	+1.576	+4.973	<.001	.009	3	3
BLCA	MTCO2P9 →	+0.072	+7.307	<.001	<.001	3	3
COAD	C4BPAP1 →	+0.206	+3.007	<.001	.009	3	2
UCEC	RN7SL248P →	+0.046	+2.783	<.001	.009	3	2
LUSC	RNU6-784P →	+0.426	+4.070	<.001	.004	3	2
LUSC	MIR503 →	+0.476	+4.150	.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,065 associations by consensus.

NCOR1P1 by SAMD4B expression — BLCA

Explore this box plot interactively →