Q-omics provides the consensus-scored C4BPAP1 profile across patient tissues and cancer cell-line models. C4BPAP1 expression is associated with patient survival in 14 of 34 cancer types, with the highest sampling consensus in READ. Among the 18 cancer types available for tumor–normal comparison, C4BPAP1 is differentially expressed in 3, with the highest sampling consensus in LIHC. Additionally, C4BPAP1 RNA expression shows 15,016 significant protein co-abundance associations, with the highest sampling consensus in LSCC. Together, these results highlight READ, LIHC, and LSCC as cancer lineages where C4BPAP1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for C4BPAP1 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes C4BPAP1 survival associations across molecular data types. C4BPAP1 RNA expression shows survival associations in the most cancer types (14). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible C4BPAP1 RNA expression–survival associations across cancer types. High C4BPAP1 expression shows unfavorable associations in READ, KICH and KIRP, but favorable associations in LIHC, LUAD and UCS. The READ Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify READ as the clearest survival context for C4BPAP1 RNA expression.
This table summarizes C4BPAP1 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 3. The strongest signals are observed in LIHC for RNA.
This table ranks reproducible tumor–normal expression differences for C4BPAP1. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. C4BPAP1 shows lower tumor expression in LUSC and THCA and higher tumor expression in LIHC. The LIHC box plot shows higher C4BPAP1 RNA expression in tumor versus normal tissue (log2 FC = +0.070, t-test p = .003).
This table shows molecular features associated with C4BPAP1 in patient tissues and cancer cell lines. In patient samples, C4BPAP1 shows the broadest associations at the RNA and protein expression levels, with LSCC recurring as the lineage with the largest associated feature set.
