Across TCGA pan-cancer cohorts, C4BPAP1 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of C4BPAP1’s most consistent transcriptional readouts.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where C4BPAP1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types C4BPAP1 is over-expressed in tumor, although a few such as LUSC and THCA show the opposite, repressed pattern.

LIHC, LUSC, and THCA are the cancer types where C4BPAP1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in C4BPAP1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LIHC	All	All	+0.070	.003	7	view →
LUSC	All	All	−0.096	<.001	6	view →
THCA	Male	III,IV	−0.032	.036	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: C4BPAP1 RNA expression & survival · all C4BPAP1 data types